Isolated luciferases and the use thereof

Details Isolated luciferases and the use thereof Isolated luciferases and the use thereof

2007-11-20

2007-11-20

Strzelecka, Teresa E. (Department: 1637)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

Reexamination Certificate

active

10416752

ABSTRACT:
This invention relates to an isolated nucleic acid molecule which is a) a nucleic acid molecule comprising SEQ ID No. 3, or b) a nucleic acid molecule which exhibits at least 90% sequence identity to the nucleic acid molecule of SEQ ID No. 3, and the claimed nucleic acid molecule encodes luciferase. It also relates to an expression vector and to a transformed host cell.

REFERENCES:
patent: 5604123 (1997-02-01), Kazami et al.
patent: 9949019 (1999-09-01), None
patent: WO9949019 (1999-09-01), None
Thomson, C.M., Herring, P.J., and Campbell, A.K.; “The Widespread Occurrence and Tissue Distribution of theImidazolopyrazine luciferins”, J. Biolumin Chemilumin, 12: 87-91 (1997).
Campbell, A.K., and Herring, P.J.; “Imidazolopyrazine bioluminescencein copepods and other marine organisms”, Marine Biology, 104: 219-225 (1990).
Inouye, S., Watanabe, K., Nakamura, H., and Shimomura, O.; “Secretational luciferase of the luminous shrimpOplophorus gracilirostris: cDNA cloning of a novelImidazopyrazinone luciferase”, FEBS Letters, 481: 19-25 (2000).
Inouye, S., Ohmiya, Y., Toya, Y., and Tsuji, F. I., “Imaging of liciferase secretion from transformed Chinese hamster ovary cells”,Proc. Natl. Acad. Sci. USA, 89: 9584-9587 (1992).
Hastings, J. W.; “Chemistries and colors of bioluminescent reactions: a review”, Gene, 173: 5-11 (1996).

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