Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Transferase other than ribonuclease
Reexamination Certificate
2005-07-26
2005-07-26
Monshipouri, Maryam (Department: 1652)
Chemistry: molecular biology and microbiology
Enzyme , proenzyme; compositions thereof; process for...
Transferase other than ribonuclease
C435S320100, C435S325000, C435S252300, C435S006120, C536S023200
Reexamination Certificate
active
06921654
ABSTRACT:
The present invention provides amino acid sequences of peptides that are encoded by genes within the human genome, the kinase peptides of the present invention. The present invention specifically provides isolated peptide and nucleic acid molecules, methods of identifying orthologs and paralogs of the kinase peptides, and methods of identifying modulators of the kinase peptides.
REFERENCES:
patent: 5858662 (1999-01-01), Keating et al.
patent: 2002/0110811 (2002-08-01), Levine et al.
Results of BLAST Search of SEQ ID No.:2 against Derwent (FastAlertP and GENESEQP) and NCBI (pataa) protein patent databases on Sep. 8, 2004 (60 pages).
Sumi et al. “Cofilin Phosphorylation and Actin Cytoskeletal Dymanics Regulated by Rho- and Cdc42-Activated Lim-Kinase 2.” Journal of Cell Biol. 1999. vol. 147, pp. 1519-1532.
Mizuno et al. “Identification of a Human cDNA Encoding a Novel Protein Kinase with Two Repeats of the LIM/Double Zinc Finger Motif.” Oncogene. 1994. vol. 9, pp. 1605-1612.
Yang et al. “Cofilin Phosphorylation by LIM-Kinase 1 and its Role in Rac-Mediated Actin Reorganization.” Naturem. 1998. vol. 393, pp. 809-812.
International Search report dated Dec. 2, 2003.
Abu-Threideh Jane
Neelam Beena
Yan Chunhua
Applera Corporation
Celera Genomics
Karjala Justin D.
Monshipouri Maryam
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