Isolated human herpesvirus type 8 sequences and uses thereof

Details Isolated human herpesvirus type 8 sequences and uses thereof Isolated human herpesvirus type 8 sequences and uses thereof

1996-02-28

1999-01-19

Mosher, Mary E.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving virus or bacteriophage

435 691, 435 693, 435 71, 435 6, 530300, 5303894, 536 2372, 536 231, 536 243, C12Q 170, C07K 1403, C07K 1608, C12N 1538

Patent

active

058612408

ABSTRACT:
Isolated human herpesvirus type 8 nucleic acid sequences expressed in latently infected human cells including primary Kaposi's sarcoma cells, primary pulmonary tumor cells, and a body cavity based lymphoma cell line are disclosed. Methods of detecting HHV-8 infection and methods of inhibiting expression of the nucleic acid sequences in vivo are also disclosed.

REFERENCES:
Muralidhar et al. J. of Virology, Jun. 1998, vol. 72, pp. 4980-4988.
Sun et al P.N.A.S.USA, 1996, vol. 93, pp. 11883-11888.
Ambroziak, J., (1995) "Herpes-Like Sequences in HIV-Infected and Uninfected Kaposi's Sarcoma Patients," Science 268:582-583.
Beral, V. et al. (1990) "Kaposi's sarcoma among persons with AIDS: a sexually transmitted infection?" Lancet 335:123-128.
Boshoff, C., et al., (1995) "Kaposi's-sarcoma-associated herpesvirus in HIV-negative Kaposi's sarcoma," Lancet 345:1043-1044.
Chang, Y., et al., (1994) "Identification of Herpesvirus-Like DNA Sequences in AIDS-Associated Kaposi's Sarcoma," Science 266:1865-1869.
DiMaio, D., (1991) "Transforming Activity of Bovine and Human Papillomaviruses in Cultured Cells," Adv. Cancer Res. 56:133-159.
Moore, P. and Chang, Y., (1995) "Detection of Herpesvirus-Like DNA Sequences in Kaposi's Sarcoma in Patients with and those without HIV Infection," New Engl. J. Med. 332:1181-1185.
Perlman, David, (1996) "Virus Implicated in Kaposi's," San Francisco Chronicle, Mar. 1, 1996, p. A4.
Petti, L., et al., (1991) "Activation of the platelet-derived growth factor receptor by the bovine papillomavirus E5 transforming protein," Embo J. 10:845-855.
Schalling, M. et al., (1995) "A role for a new herpes virus (DSHV) in different forms of Kapos's sarcoma," Nature Medicine 1(7): 707-723.
Su, I. J., et al., (1995) "Herpesvirus-like DNA sequence in Kaposi's sarcoma from AIDS and non-AIDS patients in Taiwan," Lancet 345:722-723.
Wang, D., et al., (1985) "An EBV Membrane Protein Expressed in Immortalized Lymphocytes Transforms Established Rodent Cells," Cell 43:831-840.
Whitby, D., et al., (1995) "Detection of Kaposi sarcoma associated herpesvirus in peripheral blood of HIV-infected individuals and progression to Kaposi's sarcoma," Lancet 346: 799-802.
Cesarman, E. et al., 1995, N.E.J.M. vol. 332, pp. 1186-1191.
Change, Y. et al., 1994, Science, vol. 266. pp. 1865-1869.
Boshoff, C. et al., 1995, Lancet, vol. 345. pp. 1043-1044.

Affiliated with

Also associated with

Rating

Isolated human herpesvirus type 8 sequences and uses thereof does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Isolated human herpesvirus type 8 sequences and uses thereof, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Isolated human herpesvirus type 8 sequences and uses thereof will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1245645