Isolated human enzyme proteins, nucleic acid molecules...

Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Transferase other than ribonuclease

Reexamination Certificate

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C435S069100, C435S071100, C435S320100, C435S094000, C536S023100, C536S023200

Reexamination Certificate

active

06884609

ABSTRACT:
The present invention provides amino acid sequences of peptides that are encoded by genes within the human genome, the enzyme peptides of the present invention. The present invention specifically provides isolated peptide and nucleic acid molecules, methods of identifying orthologs and paralogs of the enzyme peptides, and methods of identifying modulators of the enzyme peptides.

REFERENCES:
patent: 20020026033 (2002-02-01), Cummings et al.
patent: 20020142416 (2002-10-01), Beasley et al.
Ouyang et al. “Tyrosylprotein Sulfotransferase: Purification and Molecular Cloning of an Enzyme that Catalyzes Tyrosine O-Sulfation, a Common Posttranslational Modification of Eukaryotic Proteins.” Proceedings of the National Academy of Sciences. USA, Mar. 1998, vol. 95, pp. 2896-2901.
Ouyang et al. “Homo SapiensTyrosylprotein Sulfotransferase-1 mRNA, Complete CDs.” Database GenBank. Apr. 15, 1998. US National Library of Medicine.
Ouyang et al. “Mus Musculus Tyrosylprotein Sulfotransferase-1 mRNA, Complete CDs.” Database GenBank. Apr. 15, 1998. US National Library of Medicine.
Sulston et al. “Homo SapiensBAC Clone RP11-332L16 from 7, Complete Sequence.” Database GenBank. Mar. 1, 2002. US National Library of Medicine.
International Search report dated Jan. 9, 2003.
Results of BLAST search of SEQ ID NO:2 against Derwent (FastAlert and GeneSeqP) and NCBI (pataa) protein patent databases on Jul. 23, 2003.

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