Isolated human drug-metabolizing proteins, nucleic acid...

Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Transferase other than ribonuclease

Reexamination Certificate

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C435S252300, C435S320100, C536S027200

Reexamination Certificate

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06875597

ABSTRACT:
The present invention provides amino acid sequences of peptides that are encoded by genes within the human genome, the drug-metabolizing enzyme peptides of the present invention. The present invention specifically provides isolated peptide and nucleic acid molecules, methods of identifying orthologs and paralogs of the drug-metabolizing enzyme peptides, and methods of identifying modulators of the drug-metabolizing enzyme peptides.

REFERENCES:
patent: 9922005 (1999-05-01), None
Shworak, N.W., et al. (1997) J. Biol. Chem. 272(44), 28008-28019.*
Habuchi, O. (2000) Biochim. Biophys. Acta 1474, 115-127.

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