Isolated human cytomegalovirus polypeptides and uses thereof

Details Isolated human cytomegalovirus polypeptides and uses thereof Isolated human cytomegalovirus polypeptides and uses thereof

1995-07-25

2000-09-19

Mosher, Mary E.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving virus or bacteriophage

435 691, 435 693, 435 792, 435 794, 435975, 4241851, 4241921, 4242301, 530324, 530328, 536 2372, 930220, C12Q 170, C07H 2104, A61K 39245

Patent

active

061209899

ABSTRACT:
Diagnostically relevant polypeptides and fusion proteins comprising an amino acid sequence which originates from cytomegalovirus and corresponds to a region of the major DNA-binding protein or of the C-terminal region of the tegument protein pp150 fused with at least one further fragment from another antigenic protein of cytomegalovirus are disclosed. The major DNA-binding protein is encoded by the reading frame UL57. The poly-peptides and fusion proteins according to the invention can be used in an advantageous manner in diagnostic tests and methods for the detection of IgM antibodies against cytomegalovirus.

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