Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Hydrolase
Reexamination Certificate
2005-09-06
2005-09-06
Hutson, Richard (Department: 1652)
Chemistry: molecular biology and microbiology
Enzyme , proenzyme; compositions thereof; process for...
Hydrolase
C435S183000, C530S350000, C536S023100, C536S023200
Reexamination Certificate
active
06939700
ABSTRACT:
The present invention provides amino acid sequences of peptides that are encoded by genes within the human genome, the enzyme peptides of the present invention. The present invention specifically provides isolated peptide and nucleic acid molecules, methods of identifying orthologs and paralogs of the enzyme peptides, and methods of identifying modulators of the enzyme peptides.
REFERENCES:
patent: 5498697 (1996-03-01), Iwaki et al.
Cook et al., Human Aminoacylase-1, Journal of Biological Chemistry, vol 268 (23), Aug. 1993, pp. 17010-17017.
Biagini et al., Sequence analysis of the aminoacylase-1 family. A new proposed signature for metalloexopeptidases, Comparative Biochemistry and Physiology, vol. 128, 2001, pp. 469-481.
Iwaki et al. “Protein, DNA Coding Said Protein, and Preparation of Said Protein.” Database Patent AA, US-08-127-278-4, Mar. 12, 1996.
International Search report dated Aug. 26, 2003.
Results of BLAST search of SEQ ID No:2 against Derwent (FastAlert and GeneSeqP) and NCBI (pataa) protein patent database on Aug. 29, 2003.
Mitta M. et al.; “The Nucleotide Sequence Of Human Aminoacylase-1”; Biochimica et Biophysica ACTA, Amsterdam, NL, vol. 1174, No. 2, Aug. 19, 1993, pp. 201-203, XP002300973; ISSN: 0006-3002.
Copy of Supplementary Partial European Search Report dated Feb. 15, 2005.
Beasley Ellen M.
Di Francesco Valentina
Shao Wei
Yan Chunhua
Applera Corporation
Celera Genomics
Hutson Richard
Sun-Hoffman Lin
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