Isolated genomic polynucleotide fragments that encode human...

Details Isolated genomic polynucleotide fragments that encode human... Isolated genomic polynucleotide fragments that encode human...

2002-05-30

2008-12-23

Pak, Yong D (Department: 1652)

Chemistry: molecular biology and microbiology

Enzyme , proenzyme; compositions thereof; process for...

Hydrolase

C435S004000, C435S006120, C435S069100, C435S071100, C435S091100, C435S252300, C435S320100, C435S440000, C536S023200, C536S023100

Reexamination Certificate

active

07468266

ABSTRACT:
The invention is directed to isolated genomic polynucleotide fragments that encode human lipoprotein-associated phospholipase A2, vectors and hosts containing the fragment and fragments hybridizing to noncoding regions as well as antisense oligonucleotides to these fragments. The invention is further directed to methods of using these fragments to obtain human lipoprotein-associated phospholipase A2 and to diagnose, treat, prevent and/or ameliorate a pathological disorder.

REFERENCES:
patent: 5532152 (1996-07-01), Cousens et al.
patent: 5605801 (1997-02-01), Cousens et al.
patent: 5641669 (1997-06-01), Cousens et al.
patent: 5656431 (1997-08-01), Cousens et al.
patent: 5698403 (1997-12-01), Cousens et al.
patent: 5847088 (1998-12-01), Cousens et al.
patent: 5968818 (1999-10-01), Gloger et al.
patent: 5977308 (1999-11-01), Cousens et al.
patent: 5981252 (1999-11-01), MacPhee et al.
patent: 6045794 (2000-04-01), Cousens et al.
patent: 6099836 (2000-08-01), Cousens et al.
patent: 6146625 (2000-11-01), Cousens et al.
patent: 6203790 (2001-03-01), Cousens et al.
patent: 2001/0021379 (2001-09-01), Cousens et al.
patent: 2003/0072747 (2003-04-01), Cousens et al.
patent: 2005/0100540 (2005-05-01), Cousens et al.
patent: WO95/00649 (1995-01-01), None
Sequence Alignment.
Sequence Alignment Seq ID No. 1.
Caslake et al., Atherosclerosis, 150: 413-419, 2000.
Boyd et al., Bioorg. Med. Chem., 10: 2557-61, 2000.
Kruse et al., Am. J. Hum. Genet., 66: 1522-1530, 2000.
Hiramoto et al., Stroke, 28: 2417-2420, 1997.
Stafforini et al., J. Clin. Invest., 97: 2784-2791, 1996.
Miwa et al., J. Clin. Invest., 82: 1983-1991, 1988.
Xianqing et al., 2003, Biochem. J., 375: 351-363.
Tjoelker et al., 2000, Biochim. Biophys. Acta., 1488: 102-123.
Tjoelker et al., 1995, Nature (London) 374:549-552.

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