Isolated genomic polynucleotide fragments from chromosome 17...

Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Hydrolase

Reexamination Certificate

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C435S006120, C435S069100, C435S320100, C435S252300, C536S023200

Reexamination Certificate

active

07985571

ABSTRACT:
The invention is directed to isolated genomic polynucleotide fragments that encode human carboxypeptidase D, vectors and hosts containing the fragment and fragments hybridizing to noncoding regions as well as antisense oligonucleotides to these fragments. The invention is further directed to methods of using these fragments to obtain human Carboxypeptidase D and to diagnose, treat, prevent and/or ameliorate a pathological disorder.

REFERENCES:
patent: 5998373 (1999-12-01), Hillman et al.
Zhao et al. Apr. 23, 2005 GenBank accession AQ478151.
Breiner et al. 2001 J. Vriol. 75:143-150.
Varlamov et al. 1999, J. Biol. Chem. 274:14759-14767.
Dong et al. 1999 Neuroscience 89:1301-1317.
Ishikawa et al. 1998 Gene 215:361-370.
Birren et al. Nov. 24, 1998 GenBank accession AC006050.
Song et al. 1995 J. Biol. Chem. 270:25007-25013.
Watson et al 1992 “Recombinant DNA” 2nd edtition, pp. 137-140.

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