Isolated Epstein-Barr virus BZLF2 proteins that bind MHC class I

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues

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5303873, 435 693, C07K 100, C07K 1400, C12P 2108

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active

059257342

ABSTRACT:
Isolated viral proteins, and pharmaceutical compositions made therefrom, are disclosed which are capable of binding to a .beta. chain of a Class II Major Histocompatibility Complex antigen, thereby functioning to inhibit an antigen-specific response. The viral proteins also have superantigen-like activity, and inhibit EBV infection.

REFERENCES:
patent: 5116964 (1992-05-01), Capon et al.
08/107,353 Spriggs et al. Aug. 13, 1993.
08/145,830 Gayle et al. Oct. 29, 1993.
Baer et al., Nature 310:207; 1984.
Cohen et al., Proc. Natl. Acad. Sci. USA 81:4183, 1984.
Seible et al., Proc. Natl. Acad. Sci. USA 60:902, 1986.
Gascoigne et al., Proc. Natl. Acad. Sci. U.S.A. 84:2936, 1987.
Fanslow et al., J. Immunol. 149:65, 1992.
Noelle et al., Proc. Natl. Acad. Sci. U.S.A. 89:6550, 1992.
Hollenbaugh et al., EMBO J. 11:4313, 1992.
Marschall et al., J. Virol. 63:938, 1989.
Countryman et al., J. Virol. 61:3672, 1987.
Epstein-Barr Virus, in Fields Virology, Second Edition, 1990.
Li et al., Abstract of presentation at Cold Spring Harbor, Sep. 1994.

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