Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Patent
1995-05-30
1998-10-06
Wax, Robert A.
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
536 232, 536 241, 536 235, 435189, 4353201, C07H 2104, C12N 902
Patent
active
058177949
ABSTRACT:
Methods and compositions are provided for the production of human superoxide dismutase and a novel protocol for enhancing efficiency of expression. The gene encoding for human superoxide dismutase is isolated and inserted into a vector in conjunction with a synthetic linker which provides for enhanced efficiency in translation.
REFERENCES:
patent: 4387162 (1983-06-01), Aigle et al.
patent: 4443539 (1984-04-01), Fraser et al.
patent: 5066591 (1991-11-01), Hallewell et al.
patent: 5196335 (1993-03-01), Groner
patent: 5252476 (1993-10-01), Hallewell et al.
Hallewell et al, Nucleic Acids Research, 13:6:2017-2034 (1985).
Steinman, J. Biol. Chem., 255:14:6758-6765 (1980).
Maniatis et al, Cell, 15:687 (1978).
Gene Expression, vol. 2, Lewin, 1974, John Wiley & Sons, New York, NY, pp. 148-153.
Lieman-Hurwitz et al, Proc. Natl. Acad. Sci. USA, 79:2808-2811 (1982).
DeBoer et al, In: Promoters: Structure and Function, 1982, Praeger Publishers, New York, pp. 462-481.
Guarente et al, Science, 209:1428 (1980).
Rosenberg et al, Annual Review of Genetics, 13:319 (1979).
Beggs, Nature, 275:104 (1978).
Steitz, In: Biological Regulation and Development, vol. 1, Goldberger (ed.), 1979, Plenum Press, New York, pp. 349-357.
Sherman et al, Proc. Nat'l. Acad. Sci., 80:5456-5469 (1983).
Barra et al, FEBS Lett., 102:53 (1980).
Jabusch et al, Biochem., 19:2310 (1980).
Marklund, Proc. Natl. Acad. Sci. USA, 79:7634-7638 (1982).
Lawn et al. (1978) Cell, vol. 15, pp. 1157-1174.
Moniatis et al. (1981) Molecular Cloning (Cold Spring Harbor Laboratory, Cold Spring Harbor, N.Y.) pp. 269-328.
Hallewell Robert A.
Mullenbach Guy T.
Blackburn Robert P.
Chiron Corporation
Robins Roberta L.
Savereide Paul B.
Slobodyanky Elizabeth
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