Isolated DNA molecules for intergration site independent gene ex

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...

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4351723, 4352402, 435 6, 536 241, 800 2, C12N 516, C12N 1510, C12N 1511, C12N 1567

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055321437

ABSTRACT:
Vectors for the integration of a gene into genetic material of a mammalian host cell such that the gene may be expressed by the host cell comprise a promoter and the gene and include a dominant ectivator sequence capable of eliciting host cell-type restricted, integration site independent, copy number dependent expression of the gene.

REFERENCES:
patent: 4663281 (1987-05-01), Gillies et al.
Thiesen et al, The EMBO Journal, vol. 5 No. 4, pp. 719-724 (1986).
Storb et al, Nature, vol. 310, 1984, pp. 238-241.
Grosveld et al, Cell, vol. 51 (Dec. 1987) pp. 975-985.
Tibtech, vol. 5 (1987) pp. 20-24.
Sewell et al, PNAS USA (Nov. 1986) vol. 83, pp. 8718-8722.
Diamond et al, PNAS USA (May 1988), vol. 85 pp. 1615-1619.
D. Tuan et al PNAS, vol. 82 (Oct. 1985) pp. 6384-6388.
G. Kollias et al. Cell, vol. 46 (Jul. 4, 1986) pp. 89-94.
M. Chao et al. Cell, vol. 32 (Feb. 1983) pp. 483-493.
G. Lang et al. The EMBO J., vol. 7 No. 6 (Jun. 1988) pp. 1675-1682.
R. Palmiter et al. Mol. Cell. Bio., vol. 13 No. 9 (Sep. 1993) pp. 5266-5275.
G. Greaver et al. Cell, vol. 56 (Mar. 24, 1989) pp. 979-986.
J. Sharpe et al. Env. J. Mol. Biol., Vol. 11 ('92) pp. 4565-4571.
D. Talbot et al. Nature, vol. 338 (Mar. 23, 1989) pp. 352-355.
A. Clark et al. Tibtech, vol. 5 (Jan. '87) pp. 20-24.
C. Pittius et al. PNAS, vol. 85 (Aug. 1988) pp. 5874-5878.
G. van Assendelft et al. Cell, vol. 56 (Mar. 24, 1989) pp. 969-977.
P. Collis et al. The EMBO J., vol. 9 No. 1 ('90) pp. 233-240.
D. Gross et al. Ann. Rev. Biochem, vol. 57 (88) pp. 159-197.
R. Mulligan Science, vol. 260 ('93) pp. 926-932.
P. Marks et al. Ann. Rev. Biochem., vol. 47 ('78) pp. 419-448.
R. Jaenisch Science, vol. 240 (10 Jun. '88) pp. 1468-1474.

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