Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing compound containing saccharide radical
Reexamination Certificate
2006-02-07
2006-02-07
McKelvey, Terry (Department: 1636)
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Preparing compound containing saccharide radical
C435S243000, C435S325000, C435S419000, C435S320100, C536S023500, C536S024100
Reexamination Certificate
active
06994999
ABSTRACT:
The present invention relates to a novel promoter sequence which encodes an isolated DNA molecule comprising the polynucleotide sequence of SEQ ID NO: 1 and which encodes the promoter region of the myostatin gene, or a fragment thereof, or variant thereof which has been modified by the insertion, substitution or deletion of one or more nucleotides, said fragment and variant of said polynucleotide sequence having substantially equivalent function thereto.
REFERENCES:
Pang et al.,Partial Inverse PCR: A Technique for Cloning Flanking Sequences, Bio Techniques, vol. 22, No. 6, Jun. 1997, pp. 1046-1048.
Kambadur et al.,Cloned yeast and mammalian transcription factor TFIID gene products support basal but not activated metallothionein gene transcription, Biochemistry, vol. 87, Dec. 1990, pp. 9168-9172.
Rudnicki et al.,The MyoD Family of Transcription Factors and Skeletal Myogenesis, BioEssays, vol. 17 No. 3, 1995, pp. 203-209.
Kambadur et al.,Mutations in Myostatin(GDF8)in Double-Muscled Belgian Blue and Piedmontese Cattle, Genome Research, vol. 7, 1997, pp. 910-916.
Lassar et al.,MyoD Is a Sequence-Specific DNA Binding Protein Requiring a Region of myc Homology to Bind to the Muscle Creatine Kinase Enhancer, Cell, vol. 58, Sep. 8, 1989, pp. 823-831.
Gossett et al.,A New Myocyte-Specific Enhancer-Binding Factor That Recognizes a Conserved Element Associated with Multiple Muscle-Specific Genes, Molecular and Cellular Biology, vol. 9, No. 11, Nov., 1989, pp. 5022-5033.
Wingender, Edgar,Compilation of Transcription Regulating Proteins, Nucleic Acids Research, vol. 16, No. 5, 1988, pp. 1879-1902.
Cohen et al.,Partal Purification of a Nuclear Protein That Binds to the CCAAT Box of the Mouseα1-Globin Gene, Molecular and Cellular Biology, vol. 6, No. 3, Mar., 1986, pp. 821-832.
Bass James J.
Jeanplong Ferenc
Kambadur Ravi
Sharma Mridula
Greer Burns & Crain Ltd.
McKelvey Terry
Ovita Limited
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