Isolated DNA encoding human GP2

Details Isolated DNA encoding human GP2 Isolated DNA encoding human GP2

1994-12-06

1997-09-02

Housel, James C.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

536 231, 536 241, 435 691, 435325, 435357, 43525233, 435358, 435365, 435362, 436518, C07H 2104, C07H 2102, C12P 2106, C12N 500

Patent

active

056633157

ABSTRACT:
The invention features a method for diagnosis of pancreatitis by detecting an elevation in the amount of GP2 pancreatic glycoprotein in a sample of bodily fluid such as human blood, serum, or urine. The invention also features isolated DNA encoding human GP2, a method for producing recombinant human GP2, antibodies which specifically bind to human GP2, a method for producing anti-human GP2 antibodies, and a kit for use in the diagnosis of pancreatitis.

REFERENCES:
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Alan Tartakoff et al., "Studies on the Guinea Pig Pancreas," J. Biol. Chem. 249(23): 7420-7431, Dec. 10, 1974.
Kohler et al., "Continuous cultures of fused cells secreting antibody of predefined specificity," Nature 256:495-497, 1975.
Kohler et al., "Derivation of specific antibody-producing tissue culture and tumor lines by cell fusion," Eur. J. Immunol. 6:511, 1976.
Hubert A. Reggio et al., "Sulfated Compounds in the Zymogen Granules of the Guinea Pig Pancreas," J. Cell Biol. 77:288-314, 1978.
Linnea J. H

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