Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Lymphokines – e.g. – interferons – interlukins – etc.
Patent
1995-06-02
1999-03-02
Chan, Christina Y.
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Lymphokines, e.g., interferons, interlukins, etc.
530300, 530350, 530395, 530412, C07K 14435, C07K 1452
Patent
active
058772847
ABSTRACT:
A composition comprising a soluble peptide of about 23 kD to about 29 kD, capable of causing neutrophil and macrophage chemotaxis, and which is substantially similar to chemotactic factor from peritoneal fluid of mammals with minimal or moderate endometriosis.
REFERENCES:
Leiva et al. Am J. Obstet Gynecol 168: 592-598(1993).
Mori et al. Am J Reprod Immunol 26: 62-67(1991).
Eisermann et al. Fertil Steril 50: 573-579(1988).
Tabibzadeh Endocrine Reviews 12: 272-290 (1991).
Badawy S. Z., et al., Cellular components in peritoneal fluid in infertile patients with and without endometriosis Fertil Steril 1984 42:704.
Buttram et al. Treatment of endometrosis with Danazol Fertil Steril 1985 43:353.
Fakih et al., Interleukin-1: a possible role in the infertility associated with endometriosis Fertil Steril 1987 47:213.
American Fertility Society Revised American Fertility Society Classification of Endometriosis Fertil Steril 1985 43:351.
Halme J. et al., Increased activation of pelvic macrophages in infertile women with mild endometriosis Am J Obstet Gynecol 1983 145:133.
Halme J. et al., Peritoneal Macrophages From Patients With Endometriosis Release Growth Factor Activity in Vitro J. Clin Endocrinol Metal 1988 66:1044.
Halme J. et al., Release of Tumor Necrosis Factor-.alpha. by Human Peritoneal macrophages in vivo and invitro Am J. Obstet Gynecol 1989 161:1718.
Haney A. F., et al Reduction of the intraperitoneal inflammation associated with endometriosis by treatment with medroxyprogesterone acetate Am J. Obstet Gynecol 1988 159:450.
Leiva et al., Increased Chemotactic Activity of Peritoneal Fluid in Patients with Mild to Moderate Endometriosis Am Fertil Soc. 47th. Annual Meeting, Oct. 19-24, 1991.
Howe R.S., et al., Chemotactic Capabilities of HL-60 Human Myeloid Leukemia Cells Differentiated to Eosinophils Exp Hematol 1990 18:299.
Howe et al. Glucocorticoid and Progestin Regulation of Eosinophil Chemotactic Factor and Complement C3 in the Estrogen-Treated Rat Uterus Endocrinology 1990 126:3193.
Hill, J A et al., Lymphocyte activity in the presence of peritoneal fluid from fertile women and infertile women with and without endometriosis Am J. OBstet Gynecol 1989 161:861.
Kay G.E., et al Induction of Selective Biological Responses to Chemoattractants in a Human Monocyte-Like Cell Line Infect Immun 1983 41:1166.
Kohler and Milstein, Continuous Cultures of Fused Cells secreting antibody of predefined specificity Nature 1975 256:495.
Lee Y.H., et al Estrogen Regulation of an Eosinophil Chemotactic Factor in the Immature Rat Uterus Endocrinology 1989 125:3022.
Leiva M. et al, Increased chemotactic activity of peritoneal fluid in patients with endometriosis Am J. Obstet and Gynecol 1993 168:592.
Sundstromm C et al. Establishment and Characterization of a Human Histiocytic Lymphona Cell Line Int J. Cancer 1976 17:565.
Mori et al., Am. J. Reprod. Immunol. 1993, 168:592-598.
Tabibzadeh, Endocrine Reviews, 1991, 12:272-290.
Eiserman et al, Fertil. Steil. 1988, 50:573-579.
Chan Christina Y.
Gambel Phillip
The Trustees of the University of Pennsylvania
LandOfFree
Isolated chemotactic factor from patients with endometriosis does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Isolated chemotactic factor from patients with endometriosis, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Isolated chemotactic factor from patients with endometriosis will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-423897