Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues
Reexamination Certificate
2011-04-05
2011-04-05
Nashed, Nashaat T (Department: 1656)
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
C530S412000
Reexamination Certificate
active
07919587
ABSTRACT:
The invention relates to an isolated aquaporin having a bound ligand, wherein said ligand close the conformation of said aquaporin and inhibit and/or reduce water transport of said aquaporin, and/or a high resolution structure of an isolated aquaporin in a closed conformation characterized by the coordinates deposited at the Protein Data Bank ID:1Z98 and as set forth in Appendix 1, a crystal of said isolated aquaporin as well as the coordinates defining said crystal and the use of said aquaporin, and the use of the high-resolution structure as defined by the coordinates deposited at PDB ID:1Z98 and as set forth in Appendix 1, and a method to produce said aquaporin.
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Ekerot Maria
Hedfalk Kristina
Johansson Urban
Kjellbom Per
Neutze Richard
Hydrogene Lund AB
Merchant & Gould P.C.
Nashed Nashaat T
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