Synthetic resins or natural rubbers -- part of the class 520 ser – Synthetic resins – Mixing of two or more solid polymers; mixing of solid...
Patent
1998-02-23
1999-05-04
Lilling, Herbert J.
Synthetic resins or natural rubbers -- part of the class 520 ser
Synthetic resins
Mixing of two or more solid polymers; mixing of solid...
424 943, 435188, 436528, 514 2, 525 541, 525 50, 525 60, 525409, 528374, 530351, 530357, 530404, C08G 6348, C08G 6391, C12N 996, G01N 33544
Patent
active
059004614
ABSTRACT:
A poly(ethylene glycol) derivative is disclosed that is activated with a sulfone moiety for selective attachment to thiol moieties on molecules and surfaces. The activated PEG is water soluble, hydrolytically stable for extended periods, and forms hydrolytically stable linkages with thiol moieties. The linkages generally are not reversible in reducing environments. The PEG derivative is useful for modifying the characteristics of substances including modifying biologically active molecules and surfaces for biocompatibility. Methods for synthesizing the active PEG and for preparing conjugates of the active PEG and other substances, including biologically active substances, are also disclosed.
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Lilling Herbert J.
Shearwater Polymers, Inc.
Ware Deborah K.
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