Isoindolone compounds and their use as metabotropic...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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C546S275400

Reexamination Certificate

active

07968570

ABSTRACT:
The present invention is directed to compounds of formula I:wherein R1, R2, R3, R4, R5, R6, R7, R8, R9and n are as defined for formula I in the description. The invention also relates to processes for the preparation of the compounds and to new intermediates employed in the preparation, pharmaceutical compositions containing the compounds, and to the use of the compounds in therapy.

REFERENCES:
patent: 3993617 (1976-11-01), Schwan
patent: 5681954 (1997-10-01), Yamamoto et al.
patent: 2004/0242572 (2004-12-01), Stenkamp et al.
patent: 620 654 (1963-01-01), None
patent: 1528923 (1978-10-01), None
patent: 0 548 934 (1993-06-01), None
patent: 0602814 (1994-06-01), None
patent: 1431267 (2004-06-01), None
patent: WO-92-17448 (1991-04-01), None
patent: WO-99-26927 (1999-06-01), None
patent: WO-02-10146 (2002-02-01), None
patent: WO-03-087044 (2003-10-01), None
patent: WO-2004-024702 (2004-03-01), None
patent: WO-2004-087048 (2004-10-01), None
patent: WO-2004-089897 (2004-10-01), None
patent: WO-2005-040157 (2005-05-01), None
patent: WO-2005-074643 (2005-08-01), None
patent: WO-2005-085214 (2005-09-01), None
patent: WO-2005-085216 (2005-09-01), None
Yamamoto et al. Org. Biomol. Chem. 2004, vol. 2, pp. 1287-1294.
Morissette et al. “High-throughput crystallization: polymorphs, salts, co-crystals and solvates of pharmaceutical solids.” Advanced Drug Delivery Reviews 2004, 56, 275-300.
Souillac, et al., Characterization of Delivery Systems, Differential Scanning Calorimetry, pp. 217-218 (in Encyclopedia of Controlled Drug Delivery, 1999, John Wiley & Sons, pp. 212-227).
Vippagunta, Sudha R. “Crystalline Solids.” Advanced Drug Delivery Reviews 48(2001): 3-26.
Yamamoto et al. Org. Biomol. Chem (2004); 2,1287-1294.
CA 139:133427 Synthetic Communications 33(7), 1087-1094, 2003.
Yamamoto Y. et al: vol. 2, No. 9, May 2004, pp. 1287-1294, XP002357868.
Moreau a et al: Tetrahedron, vol. 60, No. 29, Jul. 12, 2004, pp. 6169-6176 XP002357869.
Hatt H H et al: Journal of the Chemical Society, 1952, pp. 199-205 XP002357871.
Bohme H et al: Die Pharmazie, No. 25, 1970, pp. 283-289, XP002357872.
Mori M et al: Journal of Organic Chemistry, vol. 43, No. 9, Apr. 28, 1978, pp. 1864-1867, XP002357874.
Grigg R et al: Tetrahedron Letters, vol. 44, No. 37, Sep. 8, 2003, pp. 6979-6982, XP004447066.
Norman M H et al.: Journal of Medicinal Chemistry, vol. 39, No. 1, 1996, pp. 149-157, XP000982309.
Zhuang Z-P et al: Journal of Medicinal Chemistry, vol. 41, No. 2, Jan. 15, 1998, pp. 157-166, XP002357875.
Norman M H, et al: Journal of Medicinal Chemistry, vol. 36, No. 22, Oct. 29, 1993, pp. 3417-3423, XP002357876.
Ahn K H et al: Bioorganic & Medicinal Chemistry Letters, vol. 9, No. 10, May 17, 1999, pp. 1379-1384, XP004164896.
Sugimoto H et al: Journal of Medicinal Chemistry, vol. 35, No. 24, 1992, pp. 4542-4548, XP002319779.
Mayer P et al: Journal of Medicinal Chemistry, vol. 43, Sep. 19, 2000, pp. 3653-3664, XP001183987.
Breytenbach J C et al: Bioorganic & Medicinal Chemistry Letters, vol. 10, No. 15, Aug. 7, 2000, pp. 1629-1631, XP004213210.
Anderson P S et al: Journal of Organic Chemistry, vol. 44, No. 9, 1979, pp. 1519-1515, XP002981802.
Luzzio F A et al: Tetrahedron Letters, vol. 40, No. 11, Mar. 12, 1999, pp. 2087-2090, XP002357870.
CA 133:150436, Tetrahedron Letters, 41(20), 3891-3893, 2000.
CA 83:9678, Chemical & Pharmaceutical Bulletin, 23(1), 184-187, 1975.
CA 79:105030, Roczniki Chemii, 47(5), 937-942, 1973.

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