Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2006-10-31
2006-10-31
Saeed, Kamal A. (Department: 1626)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C548S400000
Reexamination Certificate
active
07129260
ABSTRACT:
Compounds having the formulaare useful for inhibiting protein tyrosine kinases. The present invention also discloses methods of making the compounds, compositions containing the compounds, and methods of treatment using the compounds.
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Noguchi, M. Cycloaddition reaction of 2-pyrone-6-carboxamides. Bulletin of the Chemical Society of Japan, vol. 59, Issue 5, pp. 1355-1362, 1986.
Adams et al., “A strategy for the design of multiplex inhibitors for kinase-mediated signaling in angiogenesis,” Current Opinion in Chemical Biology 6(4):486-492(2002).
Rupert et al., “Suzuki couplings with phthalimidines-an efficient route to staurosporinone analogs,” Heterocycles 45(11):2217-2221 (1997).
Curtin Michael L.
Davidsen Steven K.
Frey Robin R.
Heyman Howard R.
Holms James H.
Abbott Laboratories
Chung Susannah L.
Donner B. Gregory
Saeed Kamal A.
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