Isoindolinone derivatives, production and use thereof

Details Isoindolinone derivatives, production and use thereof Isoindolinone derivatives, production and use thereof

1985-09-10

1987-09-22

Brust, Joseph Paul

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

546 19, 546122, 546200, A61K 3140, C07D20946

Patent

active

046955720

ABSTRACT:
A compound of the formula ##STR1## wherein X is hydrogen, halogen or nitro; Ar is phenyl or naphthyridinyl which may optionally be substituted; and either one of Z.sup.1 and Z.sup.2 is hydrogen and the other is lower alkanoyloxy or hydroxy, each of Z.sup.1 and Z.sup.2 is lower alkoxy, or Z.sup.1 and Z.sup.2 combinedly represent hydroxyimino, oxo or a group of the formula: ##STR2## in which Y is oxygen or sulfur and A is a branched or unbranched lower alkylene chain; and a salt thereof, act on the central nervous system but are weak in adverse effects such as hypnotic and muscle relaxant effects.

REFERENCES:
patent: 3966931 (1976-06-01), Jeanmart et al.

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