Isoindolinone derivatives, processes for preparing them and medi

Details Isoindolinone derivatives, processes for preparing them and medi Isoindolinone derivatives, processes for preparing them and medi

1989-03-06

1991-03-12

Shah, Mukund J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

514333, 514339, 544373, 546256, 546272, 548472, A61K 31495, A61K 3144, C07D40306, C07D40106

Patent

active

049993550

ABSTRACT:
Compounds of formula: ##STR1## in which: either R.sub.1 represents 4-phenyl-1,2,3,6-tetrahydro-1-pyridyl or 4-(4-fluorophenyl)-1,2,3,6-tetrahydro-1-pyridyl, R.sub.2 represents hydrogen, alkoxy of 1 or 2 carbon atoms, hydroxyl, alkyl, alkylthio, alkylcarbonyloxy, phenylalkylcarbonyloxy, phenylalkyl or --NR.sub.4 R.sub.5 in which R.sub.4 represents hydrogen or alkyl and R.sub.5 represents alkyl, phenyl, monohalogenated phenyl or pyridyl, and R.sub.3 represents a hydrogen atom, or else R.sub.2 represent phenyl and R.sub.3 represents hydrogen or hydroxyl;

REFERENCES:
patent: 3579524 (1971-05-01), Van Dyke
patent: 4505911 (1985-03-01), Dolak et al.
patent: 4585773 (1986-04-01), Dolak
patent: 4849441 (1989-07-01), Okazaki et al.
Corne et al., Psychopharmacologia 11, p. 65 (1967).
Iversen, Neuropharmacology 23, p. 1553 (1984).
Reyntjens et al., Drug Development Research 8, p. 205 (1986).
Glennon, J. Med. Chem. 30, p. 1 (1987).
Sandrini et al., European Journal of Pharmacology 130, p. 311 (1986).
Laduron in Les Antimigaineux (Masson Publishers) pp. 122-138 (1985).
Leysen et al., Neuropharmacology 23, p. 1493 (1984).
Leysen et al., Molecular Pharmacology 21, p. 301 (1982).
Van Dyke, Chemical Abstracts, vol. 72, No. 43728 (1970).
TIPS, 1987, vol. 8, p. 504.
Roelens (Dermatologica) 1989, 178, 98.
Cazzola et al., (Allergy 1990, vol. 45 (2), p. 151, Abstract).
Meuldermans et al., Arzneim. Forsch. Drug Res. 38 (1), 6, 1988.
Pharmaprojects: ZK 33 839 (Abstract).
Geller Allergy 1989, Abstract for vol. 63 (1), pp. 29-30.
Wanderer, Abstract for J. Allergy Clin. Immunol. 1986, vol. 78, p. 417.

Affiliated with

Also associated with

Rating

Isoindolinone derivatives, processes for preparing them and medi does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Isoindolinone derivatives, processes for preparing them and medi, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Isoindolinone derivatives, processes for preparing them and medi will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-448748