Isoindole derivatives, compositions containing same,...

Details Isoindole derivatives, compositions containing same,... Isoindole derivatives, compositions containing same,...

2007-09-28

2011-10-11

Desai, Rita (Department: 1625)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C514S290000

Reexamination Certificate

active

08034939

ABSTRACT:
This invention relates to isoindole derivates of Formula Ito pharmaceutical compositions comprising such derivatives, and to methods of treatment comprising administering of such derivatives.

REFERENCES:
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Dorwald F. A. Side Reactions in Organic Synthesis, 2005, Wiley: VCH, Weinheim p. IX of Preface.
Chiosis et al, A Small Molecuule Designed to Bind to the Adenine Nucleotide Pocket of Hsp90 Causes Her2 Degradation and the Growth Arrest and Differentiation of Breast Cancer Cells, Chemistry & Biology; 8 (2001) pp. 289-299.
Chiosis et al, Development of Purine-Scaffold Small Molecule Inhibitors of HSP90, Current Cancer Drug Targets, 2003, 3, pp. 371-376.

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