Isoform gene for focal adhesion protein paxillin

Details Isoform gene for focal adhesion protein paxillin Isoform gene for focal adhesion protein paxillin

1997-07-08

1998-09-22

Ketter, James

Chemistry: molecular biology and microbiology

Micro-organism, per se ; compositions thereof; proces of...

Bacteria or actinomycetales; media therefor

4353201, 436540, 530352, 536 234, 536 235, C12N 121, C12N 1570

Patent

active

058112880

ABSTRACT:
Described are cloning and sequencing of genes encoding novel isoforms (paxillins .beta. and .gamma.) of focal adhesion protein paxillin. According to the present invention, there is provided a novel gene for an isoform of focal adhesion protein paxillin. This gene is useful medical applications such as diagnosis of progress of cancer malignancy, development of a drug (cancer treatment) for preventing the metastasis and infiltration of cancer cells, etc.

REFERENCES:
Salgia et al., J. Biol. Chem, vol. 270, 1995, pp. 5039-5047.

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