Isoelectric point marker

Details Isoelectric point marker Isoelectric point marker

1980-12-18

1982-10-26

Lieberman, Allan

Chemistry: electrical and wave energy

Processes and products

Electrostatic field or electrical discharge

252408, 260112R, 260113, 260115, B01D 5702

Patent

active

043560725

ABSTRACT:
A group of compounds having the following general formula can be obtained by reacting chromoprotein and organic acid: ##STR1## wherein X is a chromophore, P is a protein, NH.sub.2 is mainly .epsilon.-amino group of lysine, n is a positive integer of 1 to 18, and m is a positive integer in the relation of m.ltoreq.n. This compound group has one to eighteen organic acids bonded thereto, and shows various isoelectric points in accordance with the number of the organic acids, but the respective isoelectric points are maintained constant. If such compounds each having an individual isoelectric point, are used as isoelectric point markers, it is possible to recognize accurately the position of isoelectric point only by a visual operation.

REFERENCES:
patent: 3712865 (1973-01-01), Evans
patent: 3764711 (1973-10-01), Melnychyn
patent: 4107014 (1978-08-01), Suzuki
Chem. Abs. 69: 57372b 69: 83978y.
H. Svensson Arch Biochem and Biophys, Supplement 1, 132-138 (1962).
Lewin Analy. Biochem. 43 394-400, 1971.
Bosshard, Experimentia vol. 32, No. 6 (1976) p. 766.

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