Isoelectric particles and uses therefore

Details Isoelectric particles and uses therefore Isoelectric particles and uses therefore

2008-07-21

2011-12-13

Lam, Ann (Department: 1641)

Chemistry: analytical and immunological testing

Involving an insoluble carrier for immobilizing immunochemicals

Carrier is organic

C436S524000

Reexamination Certificate

active

08076163

ABSTRACT:
A plurality of particles of from about 5 nm to 100 μm possessing predetermined isoelectric points in the pH range of from about 2.5 to 11 is used in a method of detection of a plurality of analytes, wherein the isoelectric particles of each isoelectric point further contain as label and a member of a binding pair capable of interacting with a selected analyte. The particles that form specific binding pairs are recovered and separated by isoelectric focusing followed by the detection of the labels associated with the particles. A flow cytometer may be used as a detector of the isoelectric particles.

REFERENCES:
patent: 4139499 (1979-02-01), Wade et al.
patent: 4954399 (1990-09-01), Tani et al.

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