Isoefrotomycin, process of preparation, pharmaceutical compositi

Details Isoefrotomycin, process of preparation, pharmaceutical compositi Isoefrotomycin, process of preparation, pharmaceutical compositi

1983-10-13

1984-11-13

Brown, Johnnie R.

Drug, bio-affecting and body treating compositions

Conjugate or complex of monoclonal or polyclonal antibody,...

Conjugated via claimed linking group, bond, chelating agent,...

424180, 536 168, 536 181, A61K 3171, C07H 306

Patent

active

044825455

ABSTRACT:
There is disclosed the novel compound isoefrotomycin which is synthesized from efrotomycin as a Michael adduct by treatment with a mixture of polar and nonpolar solvents. Isoefrotomycin is an effective antimicrobial agent and growth promotant in animals.

REFERENCES:
patent: 4024251 (1977-05-01), Maiese et al.
Wax et al, "Chem. Abst." vol. 85, 1976, p. 92146(h).
Tetrahedron Letters, 5173 (1973), No. 52, Vos.

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