Isoclavulanic acid as an antibacterial and a .beta.-lactamase in

Details Isoclavulanic acid as an antibacterial and a .beta.-lactamase in Isoclavulanic acid as an antibacterial and a .beta.-lactamase in

1975-12-08

1978-10-31

Rush, Raymond V.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Parasitic organism or component thereof or substance...

26029358, 260299, 260307FA, 424114, 424246, 42424853, 42424855, 424267, 424271, 542413, 544139, C07D49804, A61K 3142

Patent

active

041235401

ABSTRACT:
.beta.-Lactamase inhibitory and antibacterial compounds of the formula: ##STR1## wherein R is a hydrogen atom or an acyl group and salts and esters thereof, procedure for their preparation and pharmaceutical compositions containing the same.

REFERENCES:
Fuson et al., J. Am. Chem. Soc. 62, 2091 (1940).
Eliel -- "Stereochemistry of Carbon Compounds," McGraw-Hill (1962), pp. 342, 344-345.
Cole et al. -- C.A. 84, 72635t (1976): Abst. of German Offen. 2,517,346 of 10-75.

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