Isochroman derivatives

Details Isochroman derivatives Isochroman derivatives

1976-05-28

1978-01-03

Coughlan, Jr., Paul M.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260268BC, 26029355, 2603452, 424250, 544151, C07D40506

Patent

active

040666484

ABSTRACT:
New isochroman derivatives which may be represented by general formula [I] ##STR1## wherein R.sup.1 is hydrogen atom, a lower alkoxy group or hydroxyl group and R.sup.2 is a lower alkoxy group or hydroxyl group; R.sup.1 and R.sup.2 may also be, connecting with each other, alkylenedioxy group; R.sup.3 is a hydrogen atom, a lower alkyl or aralkyl group and R.sup.4 is a lower alkyl or aralkyl group; R.sup.3 and R.sup.4 may also be groups which, taken together with the adjacent nitrogen atom, form a cyclic amino group; n means 1 or 2, and pharmacologically acceptable salt thereof have antidepressant, analgesic, diuretic, anti-inflammatory, muscle relaxing, vasodilator, hypotensive and other pharmacologic activities for mammals.

REFERENCES:
patent: 3467675 (1969-09-01), Petersen et al.
patent: 3743659 (1973-07-01), Klohs et al.
patent: 3840562 (1974-10-01), Bolger et al.

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