Isethionic acid salt of 9-cyclohexyl-2-propoxy-9H-purine-6-amine

Details Isethionic acid salt of 9-cyclohexyl-2-propoxy-9H-purine-6-amine Isethionic acid salt of 9-cyclohexyl-2-propoxy-9H-purine-6-amine

1981-11-12

1983-12-06

Rivers, Diana G.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

544276, A61K 3152, C07D47318

Patent

active

044193580

ABSTRACT:
This invention concerns an isethionic acid addition salt of the non-adrenergic bronchodilating agent 9-cyclohexyl-2-propoxy-9H-purine-6-amine. The salt is comprised of a 2:1 molecular ratio of the isethionic acid to the adenine base. The salt of the invention is characterized in having improved water solubility and stability.

REFERENCES:
patent: 4057686 (1977-11-01), Fiecchi
patent: 4172829 (1979-10-01), Naito et al.
patent: 4232155 (1980-11-01), Naito et al.
patent: 4278675 (1981-07-01), Naito et al.
patent: 4286093 (1981-08-01), Temple, Jr.

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