Ischemic preconditioning

Details Ischemic preconditioning Ischemic preconditioning

1998-05-18

2000-08-15

Henley, III, Raymond

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

A61K 31495

Patent

active

061037222

ABSTRACT:
Methods and pharmaceutical compositions of matter are disclosed and claimed relating to cardioprotective effect mediated by delta (.delta.) opioid receptor agonists or more specifically delta-1 (.delta..sub.1)-opioid receptor agonists. Further, methods drawn to reducing ischemic damage to organs and tissues having delta (.delta.) opioid receptor agonists or more specifically delta-1 (.delta..sub.1)-opioid receptors are disclosed and claimed. Specifically, methods and pharmaceutical compositions of matter are taught as a means of providing cardioprotective treatment through the administration of delta (.delta.) opioid receptor agonists or more specifically delta-1 (.delta..sub.1)-opioid receptor agonists, such as TAN67(-). Said methods and pharmaceutical compositions are envisioned as a means of reducing myocardial infarction arising from the onset and sequelae of myocardial ischemia.

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