Ischaemia or hypoxia controlling compositions containing pyridin

Details Ischaemia or hypoxia controlling compositions containing pyridin Ischaemia or hypoxia controlling compositions containing pyridin

1983-02-28

1987-11-10

Jiles, Henry R.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514334, 514356, 546258, 546257, 546116, 546321, 546271, 546281, 546283, 544238, 544333, 544405, A61K 31455, C07D21300, C07D40104, C07D491048

Patent

active

047057947

ABSTRACT:
Pyridinecarboxylic acid esters of the formula ##STR1## in which R is an optionally substituted aryl or heterocyclic radical,

REFERENCES:
patent: 4497821 (1985-02-01), Wehinger et al.
patent: 4532248 (1985-07-01), Franckowiak et al.
Meyer, et al., "Nimodipine: Synthesis and Metabolic Pathway", Arzneim-Forsch. (Jan. 1983), vol. 33, pp. 106-111.
Shibanuma, et al., "Synthesis of the Metabolites of Nicardipine Hydrochloride", Chem. Pharm. Bull. (Sep. 1980), vol. 28, pp. 2609-2613.
Higuchi, et al (II), "Absorption, Excretion and Metabolism of a New Dihydropyridine", Xenobiotica, vol. 17, No. 8 (1977), pp. 469-479.
Higuchi, et al (III), "Metabolic Rate of Nicardipine Hydrochloride", Xenobiotica, vol. 10, No. 12 (1980), pp. 889-896.
Bossert, et al, "4-Aryldihydropyridines", Angew. Chem. Int. Ed. Engl. 20, 762-769 (1981).
Dzhemilev, et al, Chemical Abstracts 89:43046z (1978).
Angelova, et al., Chemical Abstracts 96:162501y (pub. 1981).
V. A. Petrow, J. Chem. Socl. 1946, pp. 884 to 888, H. Higushi et al, 95th General Congress of the Japanese Pharmaceutical Society, Apr. 1975.
S. E. Parker and J. Weinstock, Journal of Medicinal Chem. 1973, No. 1, pp. 34 to 37.
P. M. Carbateas and G. L. Williams J. Heterocyclic Chem. 11, 1974, pp. 819-821.
H. Medenwald, K. Schlossmann and C. Wunsche, Arzneim-Forsch., vol. 22, No. 1, 1972, pp. 53-56.

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