Irreversible non-steroidal antagonist compound and its use in th

Details Irreversible non-steroidal antagonist compound and its use in th Irreversible non-steroidal antagonist compound and its use in th

1997-11-25

2000-06-06

Kumar, Shailendra

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Ester doai

514150, 514508, 514617, 514618, 514619, 514620, 552 8, 558 13, 558413, 564162, 564163, 564164, 564165, 564155, A61K 31275, C07C25550

Patent

active

060719575

ABSTRACT:
The present invention relates to an antiandrogen compound and a method of treating prostate cancer in a patient utilizing the compound. The present invention also relates to a pharmaceutical composition which includes the compound.

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Tucker et al, J. Med. Chem, vol. 31, pp. 885-887, 1988.
McKillop et al, Xenobiotica, vol. 25, No. 6, pp. 623-634, 1995.
Kirkovsky et al., "Approaches to Irreversible Non-Steroidal Chiral Antiandrogens,"47th Southeast/51st Southwest Joint Regional Meeting of the American Chemical Society, Memphis, TN (Nov. 29-Dec. 1, 1995).

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