Irreversible HIV protease inhibitors, intermediates, composition

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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546169, 546268, 5483047, 544147, C07D30308, C07D21538, C07D23504, C07D41300

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active

057636311

ABSTRACT:
Cis-epoxide compounds of formula (I-3) and pharmaceutically acceptable salts, hydrates and solvates thereof: ##STR1## wherein: R.sup.1 is a cycloalkyl, or arly-substituted lower alkyl group;

REFERENCES:
patent: 5545750 (1996-08-01), Kempf et al.
patent: 5587385 (1996-12-01), Kim et al.

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