Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1995-06-07
1997-12-09
Einsmann, Margaret
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514326, 514475, 530331, A61K 3144, A61K 3147
Patent
active
056961340
ABSTRACT:
Novel cis-epoxide compounds of formula (I) are useful for treating or preventing diseases caused by HIV infection: ##STR1## wherein A, B, R.sub.1 to R.sub.4 and n have the same meanings as defined in the specification.
The novel HIV protease inhibitor of the formula (I) has a specific structure to form a stable bonding with the enzyme active site, which entails a highly enhanced irreversible inhibition against HIV protease.
Choi Ho Il
Choy Nakyen
Jung Wonhee
Kim Chung Ryeol
Kim Sang Soo
Einsmann Margaret
Hardee John R.
LG Chemical Limited
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