Irreversible HIV protease inhibitors, intermediates, composition

Details Irreversible HIV protease inhibitors, intermediates, composition Irreversible HIV protease inhibitors, intermediates, composition

1996-06-20

1998-04-28

Lambkin, Deborah

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

546169, 544168, C07D30308, C07D21538, C07D26530

Patent

active

057446210

ABSTRACT:
Cis-epoxide compounds of formula (I-1) and pharmaceutically acceptable salts, hydrates and solvates thereof: ##STR1## wherein: R.sup.1 is a cycloalkyl, or aryl-substituted lower alkyl group;

REFERENCES:
patent: 5114937 (1992-05-01), Hamby et al.
patent: 5378689 (1995-01-01), Morisawa et al.
patent: 5545750 (1996-08-01), Kempf et al.
patent: 5587388 (1996-12-01), Kim et al.

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