Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1993-11-30
1996-12-24
Gibson, Sharon
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
546169, 546175, C07D21538, A61K 3147
Patent
active
055873880
ABSTRACT:
The present invention provides cis-epoxide compounds represented by formula (I-1), (I-2) or (I-3) which are useful for treating or preventing diseases caused by HIV infection: ##STR1## wherein: A, B, D, E, R.sup.1, R.sup.10, R.sup.11, K, G, Q, r and J have the meanings as defined in the specification.
REFERENCES:
J. A. Smith, editor, Peptides, Chemistry and Biology, Proceedings of the 12th American Peptide Symposium, Jun. 16-21, 1991, Cambridge, Mas., US, 1992, ESCOM, Leiden, pp. 781-782.
W. R. Roush et al., J. Org. Chem., vol. 52, No. 23, pp. 5127-5136 (1987).
Moelling et al., Febs Letters 261, 373 (1990).
Pal et al., Proc. Natl. Acad. Sci. USA 85, 9283 (1988).
Grant et al., Bioorg. Med. Chem. Letter 2, 1441 (1992).
Choi Ho I.
Choy Nakyen
Kim Sang S.
Kim Sung C.
Koh Jong S.
Gibson Sharon
Kilby Scalzo Catherine
Lucky Limited
Pinsak William F.
LandOfFree
Irreversible HIV protease inhibitors, intermediates, composition does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Irreversible HIV protease inhibitors, intermediates, composition, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Irreversible HIV protease inhibitors, intermediates, composition will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1178776