Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues – Tripeptides – e.g. – tripeptide thyroliberin – etc.
Reexamination Certificate
2007-10-09
2007-10-09
Page, Thurman K. (Department: 1621)
Chemistry: natural resins or derivatives; peptides or proteins;
Peptides of 3 to 100 amino acid residues
Tripeptides, e.g., tripeptide thyroliberin , etc.
C558S166000, C560S155000, C562S553000
Reexamination Certificate
active
10485723
ABSTRACT:
Presented are compounds represented by the following general formulas (I) and (II), for inhibiting cysteine protease legumain for modulating associated disease states in subjects
REFERENCES:
patent: 0 995 756 (2000-04-01), None
patent: WO95/23222 (1995-08-01), None
patent: WO99/48910 (1999-09-01), None
Demuth, et al.; “Molecular drug research: A survey of the mechanism-oriented serine protease inhibitors”;Pharmazie; (1989) 44(1), 1-11 (including abstract in English).
Dando, et al.; “Pig Kidney Legumain: an asparaginyl endopeptidase with restricted specificity”;Biochem. J. ; (1999) 339, 743-749.
Ackermann, E. et al.; “Untersuchungen zur zentralnervösen Wirkung der Hydrazinoessigsäure and Ihrer Derivate”;ACTA Biological et Medica Germanica; (1964) 12, 322-341 (including summary in English).
Gante, J; “Azapeptides”;Synthesis; (1989) 405-413.
Manoury, et al.; “An asparaginyl endopeptidase process a microbial antigen for class II MHC presentation”;Nature; (1998) 396, 695-699.
International Search Report dated Feb. 26, 2003.
Demuth Hans-Ulrich
Gerhartz Bernd
Heiser Ulrich
Hoffmann Matthias
Niestroj Andre
Page Thurman K.
Probiodrug (AG)
Sonnenschein Nath & Rosenthal LLP
Valenrod Yevgeny
LandOfFree
Irreversible cysteine protease inhibitors of legumain does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Irreversible cysteine protease inhibitors of legumain, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Irreversible cysteine protease inhibitors of legumain will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3865437