Drug – bio-affecting and body treating compositions – Fermentate of unknown chemical structure – Having a known elemental analysis
Patent
1986-08-26
1988-02-23
Rosen, Sam
Drug, bio-affecting and body treating compositions
Fermentate of unknown chemical structure
Having a known elemental analysis
435 2, A61K 3514
Patent
active
047269499
ABSTRACT:
A thin film of white blood cells is irradiated with ultraviolet radiation predominately of a wavelength of 280 to 320 nanometers, and preferably at an intensity of 4 to 15 milliwatts per square cm. At such a radiation intensity it is not necessary to agitate the thin film of white blood cells to accomplish the purposes of this invention. The white blood cells so processed substantially lose their capability to set off an immune reaction in an alloimmunized patient. The white blood cells may preferably be placed into such film in a flat, flexible bag made of poly(ethylene-vinyl acetate) plastic, with the flat, flexible bag being stretched in a direction normal to the path of ultraviolet radiation.
REFERENCES:
patent: 4608255 (1986-08-01), Kahn et al.
patent: 4612007 (1987-09-01), Edelson
Bredberg et al-Chem. Abst., vol. 101 (1984), p. 146,941h.
Langner et al-Chem. Abst., vol. 88 (1978), p. 31915y.
Lynch et al.-Chem. Abst., vol. 99 (1983), p. 172086t.
Krylenkov et al-Chem. Abst., vol. 101 (1984), p. 206,812d.
Bilstad Arnold
Foley John
Glash Dean
Miripol Jeffrey E.
Baxter Travenol Laboratories Inc.
Ellis Garrettson
Flattery Paul C.
Price Bradford R. L.
Rosen Sam
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