Drug – bio-affecting and body treating compositions – Whole live micro-organism – cell – or virus containing – Genetically modified micro-organism – cell – or virus
Patent
1994-06-23
1997-06-10
Stone, Jacqueline M.
Drug, bio-affecting and body treating compositions
Whole live micro-organism, cell, or virus containing
Genetically modified micro-organism, cell, or virus
4353201, 514 44, 935 57, 935 62, 935 71, A61K 4800, C12N 1500
Patent
active
056374836
ABSTRACT:
A method of altering the specific, systemic immune response of an individual to a target antigen by the co-administration of a cytokine an adhesion or accessory molecule and the target antigen. The target antigen may be a tumor cell, a tumor cell antigen, an infectious agent or other foreign antigen, or other antigens to which an enhanced systemic immune response is desirable. Alternatively, the antigen may be a non-foreign antigen when a suppression of a systemic immune response is desired. The resulting systemic immune response is specific for the target antigen.
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Dranoff Glenn
Mulligan Richard C.
Pardoll Drew
Halluin Albert P.
Hogue, Jr. Dale Curtis
Johns Hopkins University School of Medicine
Stone Jacqueline M.
Whitehead Institute for Biomedical Research
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