Irradiated implantable bone material

Details Irradiated implantable bone material Irradiated implantable bone material

2011-07-12

2011-07-12

Schuberg, Laura (Department: 1657)

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Implant or insert

C623S023630, C264S028000, C264S488000

Reexamination Certificate

active

07976861

ABSTRACT:
A method for making an implantable bone material. The method includes providing a bone composition consisting essentially of demineralized human bone, and irradiating the composition at a temperature less than about 0° C.

REFERENCES:
patent: 4172128 (1979-10-01), Thiele et al.
patent: 4191747 (1980-03-01), Scheicher
patent: 4678470 (1987-07-01), Nashef et al.
patent: 5073373 (1991-12-01), O'Leary et al.
patent: 5123925 (1992-06-01), Smestad et al.
patent: 5171574 (1992-12-01), Kuberasampath et al.
patent: 5236456 (1993-08-01), O'Leary et al.
patent: 5290558 (1994-03-01), O'Leary et al.
patent: 5314476 (1994-05-01), Prewett et al.
patent: 5348788 (1994-09-01), White
patent: 5405390 (1995-04-01), O'Leary et al.
patent: 5455100 (1995-10-01), White
patent: 5487933 (1996-01-01), White
patent: 5507813 (1996-04-01), Dowd et al.
patent: 5531791 (1996-07-01), Wolfinbarger, Jr.
patent: 5674292 (1997-10-01), Tucker et al.
patent: 5730933 (1998-03-01), Peterson
patent: 5904718 (1999-05-01), Jefferies
patent: 6013856 (2000-01-01), Tucker et al.
patent: 6123731 (2000-09-01), Boyce et al.
patent: 6180606 (2001-01-01), Chen et al.
patent: 6231608 (2001-05-01), Stone
patent: 6437018 (2002-08-01), Gertzman et al.
patent: 6440444 (2002-08-01), Boyce et al.
patent: 6461630 (2002-10-01), Tucker et al.
patent: 6504079 (2003-01-01), Tucker et al.
patent: 6565884 (2003-05-01), Nimni
patent: 6576249 (2003-06-01), Gendler et al.
patent: 6679918 (2004-01-01), Benedict et al.
patent: 7678385 (2010-03-01), Reddi
patent: 2001/0018614 (2001-08-01), Bianchi
patent: 2001/0031254 (2001-10-01), Bianchi et al.
patent: 2003/0074065 (2003-04-01), Stone
patent: 2003/0143258 (2003-07-01), Knaack et al.
patent: 2003/0236573 (2003-12-01), Evans et al.
patent: 2004/0037735 (2004-02-01), DePaula et al.
patent: 2004/0059364 (2004-03-01), Gaskins et al.
patent: 2004/0091459 (2004-05-01), Nimni
patent: 2005/0244450 (2005-11-01), Reddi
patent: WO 03/051240 (2003-06-01), None
Dziedzic-Goclawska et al. “Effect of Radiation Sterilization on the Osteoinductive Properties and the Rate of Remodeling of Bone Implants Preserved by Lyophilization and Deep-Freezing”, Clin Orthop Rel Res, 1991, Dec., vol. 272 pp. 30-37.
Izawa et al., “The effect of heat-treated human bone morphogenetic protein on clinical implantation”, Clin Ortho Rel Res 390, 2001, pp. 252-258.
Katz et al., “Radiation-sterilized insoluble collagenous bone matrix is a functional carrier of osteogenin for bone induction”, Calcif Tissue Int, 1990, Sep.; 47(3): 183-5.
Leikina et al., “Type I collagen is thermally unstable at body temperature”, PNAS, Feb. 5, 2002, vol. 99, No. 3, pp. 1314-1318.
Lewandrowski et al., “An electron microscopic study on the process of acid demineralization of cortical bone”, Calcif Tissue Int 61, 1997, pp. 294-297.
Lewandrowski et al., “Improved osteoinduction of cortical bone allografts: a study of the effects of laser perforation and partial demineralization”, J Orthop Res 15, 1997, pp. 748-756.
Lewandrowski et al., “Kinetics of cortical bone demineralization: controlled demineralization—a new method for modifying cortical bone allografts”, J Biomed Mater Res 31, 1996, pp. 365-372.
Munting et al., “Effect of sterilization on osteoinduction. Comparison of five methods in demineralized rat bone”, Acta Orthop Scand, 1988, Feb; 59(1): 34-8.
Reddi et al., “Biochemical sequences in the transformation of normal fibroblasts in adolescent rats”, Proc Nat Acad Sci 69, 1972, pp. 1601-1605.
Sato et al., “Heat tolerance of activity toward ectopic bone formation by rabbit bone matrix protein”, Ann Chir Gynaecol Suppl 207, 1993, pp. 37-40.
Urist et al., “Exicitation transfer in bone. Deleterious effects of cobalt 60 radiation-sterilization of bank bone”, Arch Surg, 1974, Oct.; 109(4): 486-93.
Weintroub et al., “Influence of irradiation on the osteoinductive potential of demineralized bone matrix”, Calcif Tissue Int 42, 1988, pp. 255-260.
Mellonig et al., “Tissue Banking and Periodontal Bone Allografts” Committee on Research Science and Therapy, Apr. 1994, pp. 1-6.

Affiliated with

Also associated with

Rating

Irradiated implantable bone material does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Irradiated implantable bone material, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Irradiated implantable bone material will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2649276