Iron-tetraphenylporphine complex having phosphocholine group

Details Iron-tetraphenylporphine complex having phosphocholine group Iron-tetraphenylporphine complex having phosphocholine group

1983-11-28

1985-07-23

Raymond, Richard L.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

424 38, C07D48722, C09B 4700

Patent

active

045307946

ABSTRACT:
Disclosed is an iron-5,10,15,20-tetra(.alpha., .alpha., .alpha., .alpha.-o-substituted phenyl)porphine complex having one or four substituents with a phosphocholine group at the terminal end thereof. The substituents are positioned ortho of the phenyl group or groups.

REFERENCES:
patent: 4133874 (1979-01-01), Miller et al.
patent: 4356167 (1982-10-01), Kelly
Hasegawa et al, "Liposomal Heme as Oxygen Carrier under Semiphysiological Condition", Biochem. and Biophys. Res. Communications, vol. 105, 1416-1419 (1982).
Chemistry Letters, No. 9, 1983, The Chemical Society of Japan, "Synthesis of Amphiphilic Porphinato Iron Complexes having Phosphorylcholine Groups", Yoh-ichi Matsushita et al, pp. 1387-1390.
Journal of the American Chemical Society, 97:6, pp. 1427-1439 (1975), Collman, et al.
Tetrahedron Letters, vol. 23, No. 10, pp. 1043-1046 (1982) Chandrakumar, et al.
Synthesis; pp. 517-518 (1975); Newkome, et al.

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