Iontotherapeutic device and process and iontotherapeutic unit do

Details Iontotherapeutic device and process and iontotherapeutic unit do Iontotherapeutic device and process and iontotherapeutic unit do

1987-05-07

1991-08-27

Cohen, Lee S.

Surgery

Means for introducing or removing material from body for...

Infrared, visible light, ultraviolet, x-ray or electrical...

128803, A61N 130

Patent

active

050429752

ABSTRACT:
This invention relates to development of an iontotherapeutic device for regulated transdermal systemic administration of ionizable pharmaceutical compounds.
It also provides an iontotherapeutic process for transdermal administration of ionized pharmaceuticals, particularly those which are otherwise transdermally absorbed to a small degree or not all, such as peptide pharmaceuticals, for example, insulins. The invention also relates to unit dose forms, for example, those in which an ionized pharmaceutical is dispersed in a hydrophilic polymer. The unit dose is adapted to be assembled as part of the pharmaceutical reservoir electrode, so that the ionized pharmaceutical will be delivered transdermally and then be absorbed systemically when the iontotherapeutic device is in operation.

REFERENCES:
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patent: 4149533 (1979-04-01), Ishikawa et al.
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patent: 4462274 (1983-11-01), Jacobsen et al.
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patent: 4708716 (1987-11-01), Sibalis
patent: 4764164 (1988-08-01), Sasaki
patent: 4786277 (1988-11-01), Powers et al.
Journal of Controlled Release, 4(1986) 79-85 Keiichiro Okabe et al.

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