Surgery – Means for introducing or removing material from body for... – Infrared – visible light – ultraviolet – x-ray or electrical...
Reexamination Certificate
2007-03-13
2011-10-11
Stigell, Theodore (Department: 3767)
Surgery
Means for introducing or removing material from body for...
Infrared, visible light, ultraviolet, x-ray or electrical...
C604S890100, C604S501000
Reexamination Certificate
active
08036738
ABSTRACT:
An iontophoretic transdermal drug delivery system that utilizes a porous conductive polyaniline membrane as one of two electrodes, with both electrodes in contact with an aqueous solution of the ingredient in ionic and nonionic form, and the membrane additionally in contact with the skin surface of the mammal. Upon providing the appropriate direct current flow by voltage generating means through the electrodes and solution, the ingredient is caused to pass through the porous membrane and be released in ionic form through the skin surface of the mammal.
REFERENCES:
patent: 3991755 (1976-11-01), Vernon et al.
patent: 3993072 (1976-11-01), Zaffaroni
patent: 3993073 (1976-11-01), Zaffaroni
patent: 4031894 (1977-06-01), Urquhart
patent: 4141359 (1979-02-01), Jacobsen et al.
patent: 4262003 (1981-04-01), Urquhart
patent: 4585652 (1986-04-01), Miller et al.
patent: 4722726 (1988-02-01), Sanderson et al.
patent: 4731049 (1988-03-01), Parsi
patent: 4927408 (1990-05-01), Haak et al.
patent: 5057072 (1991-10-01), Phipps
patent: 5084008 (1992-01-01), Phipps
patent: 5096586 (1992-03-01), Kaner et al.
patent: 5125894 (1992-06-01), Phipps et al.
patent: 5135477 (1992-08-01), Untereker et al.
patent: 5484884 (1996-01-01), MacDiarmid et al.
patent: 6004309 (1999-12-01), Phipps
patent: 6049733 (2000-04-01), Phipps et al.
patent: 6195582 (2001-02-01), Scott
patent: 6273875 (2001-08-01), Siman et al.
patent: 6330471 (2001-12-01), Higo et al.
patent: 2002/0022826 (2002-02-01), Reynolds et al.
patent: 2004/0176737 (2004-09-01), Henley et al.
patent: 2004/0193089 (2004-09-01), Fischer et al.
patent: 2004/0248320 (2004-12-01), Santini et al.
patent: 2005/0266568 (2005-12-01), Fujihara et al.
patent: 2007/0255195 (2007-11-01), Adachi
Q. Fan, K. K. Sirkar, Y. Wang, B. Michniak,In vitro delivery of doxycycline hydrochloride based on a porous membrane-based aqueous-organic partitioning system, J. Controlled Release, 98 (3) (2004) 355-365.
Q. Fan,In Vitro Drug Delivery Based on Porous Membrane-Based Aqueous-Organic Partitioning System and It's Enhancements Through Mouse Skin, A Dissertation Submitted to the Faculty of New Jersey Institute of Technology in Partial Fulfillment of the Requirement for the Degree of Doctor of Philosophy, (Jan. 2005) 1-93.
Zhou Qin-Xin,Ion Delivery From Conducting Polymer-Polypyrrole, A Thesis Submitted to the Faculty of the Graduate School of the University of Minnesota in Partial Fulfillment of the Requirements for the Degree of Doctor of Philosophy in Chemistry, (Jul. 5, 1987) 1-194.
Chang, An-Cheng,Characterization and Properties of Oligomers of 3-Methoxythiophene, A Thesis Submitted to the Faculty of the Graduate School of the University of Minnesota in Partial Fulfillment of the Requirements for the Degree of Doctor of Philosophy, (Jul. 1987), 1-211.
C. R. Wilke, et al.,Correlation of Diffusion Coefficients in Dilute Solutions, AIChE J. I (1955) 264-270.
Kratohvil, et al.,The Influence of the Composition and the Properties of the Solvent on Complex Formation Between Silver and Chloride, Bromide, Iodide, and Thiocyanate Ions, Recueil des Travaux Chimiques des Pays-Bas et de la Belgique, 75 (1956) 774-780.
P. Anderson, et al.,The Solubility of Silver Chloride and the Concentration of Silver-Containing Species in Ethanol-Water Mixtures, J. Physical Chemistry, 71 (11) (1967) 3566-3569.
J. S. Newman,Electrochemiical Systems, Prentice-Hall, Englewood Cliffs, New Jersey, pp. 227, Table 75-1,1973.
J. B. Bogardus, et al..,Solubility of Doxycycline in Aqueous Solution, J. Pharm. Sci. 68 (1979) 188-194.
R. Prasad, et al.,Dispersion-Free Solvent Extraction With Microporous Hollow-Fiber Modules, AIChE. J. 44 (1988) 177-188.
J. B. Phipps, et al.,Iontophoretic Delivery of Model Inorganic and Drug Ions, J. of Pharm. Sci. 78(5) (1989) 365-369.
K. A. Walters, et al.,Penetration Enhancers and Their Use in Transdermal Therapeutic Systems, Transdermal Drug Delivery, Developmental Issues and Research Initiatives, Marcel Dekker, Inc., New York, 1989, Chapter 10.
MMWR, Recommendations and Reports,Recommendations for the Prevention ofMalaria Among Travelers, Morbidity and Mortality Weekly Report, 39 (RR-3) (1990) 1-10.
M. J. Pikal,The Role of Electroosmotic Flow in Transdermal Iontophoresis, Advanced Drug Delivery Reviews, 9 (2-3) (1992) 201-237.
P. Singh, H. et al.,Iontophoresis in Drug Delivery: Basic Principles and Applications, Critical Reviews in Therapeutic Drug Carrier Systems, II (2&3) (1994) 161-213.
H. SjÖberg, et al.,Ionization Conditions for Iontophoretic Drug Delivery. A Revised Pka of Lidocaine Hydrochloride in Aqueous Solution At 25° C. Established by Precision Conductometry, Int. J Pharm. 141 (1996) 63-70.
S. Farrell,A Controlled Release Technique Using MicroporousMembranes, Ph. D. Dissertation, New Jersey Institute of Technology, 1996.
J. E. Riviere, et al.t,Electrically-Assisted Transdermal Drug Delivery, Pharm. Research, 14 (6) (1997) 687-697.
K. Kararni, et al.,Ionization Conditions for Iontophoretic Drug Delivery. Electrical Conductance and Aggregation of Lidocaine Hydrochloride in 1-Octanol At 25° C., Int. J Pharm. 154 (1997) 79-87.
S. Farrell, et al.,A Reservoir-Type Controlled Release Device Using Aqueous-Organic Partitioning and a Porous Membrane, J. Membr. Sci. 130 (1997) 265-274.
K. Banga,Iontophoretic Transdermal Drug Deliveryin Electrically Assisted Transdermal and Topical Drug Delivery (Chapter 2), Taylor & Francis Inc., London, UK, 1998, Chapter 2.
M. Cheryan,Ultrafiltration and Microfiltration Handbook, CRC Press, Boca Raton, FL, 1998.
H. Chen, et al.,Selective C02 Separation From C02-N2 Mixtures by Immobilized Carbonate-Glycerol Membranes, Industrial and Engineering Chemistry Research 38(9) (1999) 3489-3498.
L. Wen, et al.,Doping-dependent ion selectivity of polyaniline membranes, Syn. Metals, 106 (1999) 19-27.
S. Farrell, et al.,A Mathematical Model of an Aqueous-Organic Partition-Based Controlled Release System Using Microporous Membranes, J. Controlled Rel. 61 (1999) 345-360.
R. Panchagnula, et al.,Transdermal Iontophoresis Revisited, Current Opinion in Chemical Biology, 4 (2000) 468-473.
D. Marro, et al.,Optimizing Iontophoretic Drug Delivery: Identification and Distribution of the Charge-Carrying Species, Pharm. Res. 18 (12) (2001) 1709-1713.
G. Illing, et al.,Preparation and Characterization of Polyaniline Based Membrane for Gas Separation, J. Membrane Sci., 184 (2001) 69-78.
S. B. Kessler, et al.,Definitions, Membrane Handbook, Chapman and Hall, New York, 1992, Chapter 11; Kluwer Academic, Boston (2001).
S. Farrell, K. et al.,Mathematical Model of a Hybrid Dispersed Network-Membrane-Based Controlled Release System, J. Controlled Rel. 70 (2001) 51-61.
P. Wang, et al.,Preparation and Characterization of Semi-Conductive Poly(Vinylidene Fluoride)/Polyaniline Blends and Membranes, Applied Surfaces Sciences, 193 (2002) 36-45.
W. E. Rhodes III,Iontophoretic Drug Delivery: New Advantages Revitalize an Established Technology, Drug Delivery Technology, 2 (6) (2002), 34-37.
Mirmohseni, et al.,Preparation and Characterization of Aqueous Polyaniline Battery Using a Modified Polyaniline Electrodes, Euro. Polym. J., 39 (2003) 219-223.
Y. Wang, et al.,Effects of Fatty Acids and Iontophoresis on the Delivery of Midodrine Hydrochloride and the Structure of Human Skin, Pharm. Res. 20 (2003) 1612-1618.
C. Williams, et al.,Penetration Enhancers, Adv. Drug Del. Rev., 56 (2004) 603-618.
Y. N. Kalia, et al.,Iontophoretic Drug Delivery, Adv. Drug Del. Rev. 56 (2004) 619-658.
A. Luzardo-Alvarez, Iontophoretic Delivery of Ropinirole Hydrochloride: Effect of Current Density and Vehicle Formulation, Pharmaceutical Research, vol. 18, No. 12, Dec. 2001.
Personal communication with Dr. Per Beronius, Sep. 13, 2004.
Fan Qiuxi
Sirkar Kamalesh K.
McCarter & English LLP
New Jersey Institute of Technology
Scott Brandy C
Stigell Theodore
LandOfFree
Iontophoretic transdermal drug delivery system based on... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Iontophoretic transdermal drug delivery system based on..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Iontophoretic transdermal drug delivery system based on... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-4261120