Iontophoretic drug delivery system, including method for activat

Details Iontophoretic drug delivery system, including method for activat Iontophoretic drug delivery system, including method for activat

1996-09-27

1998-08-25

Bockelman, Mark

Surgery

Means for introducing or removing material from body for...

Infrared, visible light, ultraviolet, x-ray or electrical...

607153, A61N 130

Patent

active

057978670

ABSTRACT:
The user activated iontophoretic device of the present invention includes a disposable patch and a reusable controller. The patch contains an electrode assembly, an electrode reservoir and at least one drug reservoir. The patch is divided or otherwise separated into at least two portions, with one portion containing the electrode reservoir and the other containing the drug reservoir, which may include a medication in a dry form. The electrode reservoir and the drug reservoir are sealingly separated by a barrier, which can be manipulated to bring the reservoirs into fluid conducting contact with one another. A method of activating the device includes causing the two portions to rotate about a central axis relative to one another to manipulate the barrier and bring the reservoirs into fluid conducting contact with one another to at least partially hydrate one of the reservoirs. In this way, the device is suitable for use to deliver a drug which has limited stability in an aqueous solution.

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patent: 5128137 (1992-07-01), Muller et al.
patent: 5310404 (1994-05-01), Gyory et al.
patent: 5423739 (1995-06-01), Phipps et al.
patent: 5445609 (1995-08-01), Lattin et al.
patent: 5662925 (1997-09-01), Ebert et al.

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