Iontophoretic drug delivery device having high-efficiency DC-to-

Surgery – Means for introducing or removing material from body for... – Infrared – visible light – ultraviolet – x-ray or electrical...

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607 62, A61N 130

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active

061673013

ABSTRACT:
An iontophoresis system includes a transdermal patch for placement against the skin of a patient and a controller electrically connected to the patch. The patch includes an anode and cathode electrode, and holds an electrolyte and a medication. The controller includes a DC--DC converter circuit which generates an output voltage that is provided to the anode electrode. The controller also includes an adjustable current regulator circuit. The current regulator circuit is coupled to the cathode electrode and is adjustable to provide a desired current flow through the electrodes and the skin of the patient. The DC--DC converter circuit is responsive to the voltage drop across the electrodes and adjusts its output voltage in response to this voltage drop and changes in the impedance of the patient's skin.

REFERENCES:
patent: 4141359 (1979-02-01), Jacobsen et al.
patent: 5047007 (1991-09-01), McNichols et al.
patent: 5246418 (1993-09-01), Haynes et al.
patent: 5254081 (1993-10-01), Maurer et al.
patent: 5499967 (1996-03-01), Teillaud et al.

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