Surgery – Means for introducing or removing material from body for... – Infrared – visible light – ultraviolet – x-ray or electrical...
Patent
1993-06-30
1995-01-31
Rosenbaum, C. Fred
Surgery
Means for introducing or removing material from body for...
Infrared, visible light, ultraviolet, x-ray or electrical...
607151, A61N 130
Patent
active
053855434
ABSTRACT:
A dry-state iontophoretic drug delivery device (10, 20) is provided. The device has drug and electrolyte reservoirs (15, 16) which are initially in a non-hydrated condition. In one embodiment of the invention, a passageway (21, 22) is provided through the backing layer (13) and the electrode layer (11, 12) of both the donor electrode assembly (8) and the counter electrode assembly (9). Water or other liquid can be introduced through these passageways (21, 22) in order to hydrate the drug and electrolyte reservoirs (15, 16) and activate the device (10). In another embodiment of the device (20), the drug and electrolyte reservoirs (15, 16) are initially separated from their respective electrodes (11, 12). After the reservoirs (15, 16) are hydrated, they are placed in electrical contact with their respective electrodes (11, 12). By joining the reservoir (15, 16) to the electrode (11, 12) after hydration occurs, delamination problems are reduced.
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Dorland's Pocket Medical Dictionary, 23rd Ed., p. 362; W. B. Saunders Company.
"Esperimentelle Studien iiber Elektroendosmose an uber lebender menschlicher Haut" by Von Hermann Rein, Jan. 7, 1924; Zeitschrift fur Biologie Bd. SI., J. F. Lebmanns Verlag, Munchen 1924.
Gyory J. Richard
Haak Ronald P.
Myers Robert M.
Theeuwes Felix
ALZA Corporation
Mandell Edward L.
Miller D. Byron
Rafa Michael
Rosenbaum C. Fred
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