Iontopheretic system for stimulation of tissue healing and regen

Surgery: light – thermal – and electrical application – Light – thermal – and electrical application – Electrical therapeutic systems

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604 20, A61M 532

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active

058140948

ABSTRACT:
An iontophoretic system for promoting tissue healing processes and inducing regeneration. The system includes a device and a method, a composition, and methods for making the composition in vitro and in vivo. The system is implemented by placing a flexible, silver-containing anode in contact with the wound, placing a cathode on intact skin near the anode, and applying a wound-specific DC voltage between the anode and the cathode. Electrically-generated silver ions from the anode penetrate into the adjacent tissues and undergo a sequence of reactions leading to formation of a silver-collagen complex. This complex acts as a biological inducer to cause the formation in vivo of an adequate blastema to support regeneration.

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