Ionizable congeners of aromatic and aliphatic alcohols as anti-l

Details Ionizable congeners of aromatic and aliphatic alcohols as anti-l Ionizable congeners of aromatic and aliphatic alcohols as anti-l

1994-08-08

1997-03-11

Weddington, Kevin E.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514182, A61K 31355, A61K 3156

Patent

active

056101805

ABSTRACT:
Ionizable congeners of aromatic and aliphatic alcohols provide potent cytoprotective properties in vivo and in vitro. Alpha-tocopherol succinate, cholesteryl succinate, cholesteryl sulfate, dihydrocholesterol succinate, dihydrocholesterol sulfate, and ergosterol analogs are particularly good cytoprotective agents. In addition, the tris salts of these compounds have superior cytoprotective properties.

REFERENCES:
Prasad et al., "Biological rationale of using alph-tocopherol (vitamin E) in the treatment of cancer" (1983) see abstract enclosed.

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