Ionically crosslinked carboxyl-containing polysaccharides for ad

Details Ionically crosslinked carboxyl-containing polysaccharides for ad Ionically crosslinked carboxyl-containing polysaccharides for ad

1994-02-04

1996-07-02

Kight, John

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

514 54, 514 55, 514 56, 514 57, 514 59, 514 60, 514 62, 536119, 536121, A61K 31715, C07H 1302

Patent

active

055322212

ABSTRACT:
A method of reducing post-operative adhesion formation by topically applying an ionically crosslinked carboxyl-containing polysaccharide or a pharmacologically acceptable salt thereof, e.g. sodium hyaluronate crosslinked with ferric chloride, to a site of surgical trauma.

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Chem. Abstracts 114 (10):88722t A. Galatik, "Pharmaceutical preparation based on hyaluronic acid alkali metal salt complexes with multivalent metals", 1989.
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Chem Abst CA 100(6) ;36049v M. Mozisek Crosslinked, 1983. Carboxymethyl Cellulose with High Sorption Capacity.
Derwent AN 86-282502 abstract of JP-A-61 207 328, 1986 (Taisho Parmaceut. KK).
Derwent AN 79-32582B abstract of JP-A-54 036 388, 1979 (Submitomo Elec. Ind. KK).
J. Kost, "Chemically-modified polysaccharides for enzymatically-controlled oral drug delivery", Biomaterials vol. 11, Nov. 1990, pp. 695-698.
Schmut et al., Graefe's Arch Clin Exp Ophthalmol (1982) 218:311-314.

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