Ionically conductive polymeric composition

Details Ionically conductive polymeric composition Ionically conductive polymeric composition

2005-02-15

2005-02-15

Gupta, Yogendra N. (Department: 1751)

Surgery: light, thermal, and electrical application

Light, thermal, and electrical application

Electrical energy applicator

C607S121000, C607S120000, C607S005000, C607S007000, C607S008000, C252S500000, C252S511000, C252S518100, C523S103000, C523S122000, C128S899000

Reexamination Certificate

active

06856840

ABSTRACT:
An ionically conductive polymeric composition is disclosed. The composition is especially useful for coating an implantable hot can defibrillator electrode. The polymeric composition, for example, polyethylene oxide containing NaCl or a similar ionic medium, can be used to coat and fill the pores of a high surface area electrode to provide a continuous ionic network from the can to the adjacent body tissue. The conductive polymeric composition is biocompatible, chemically and mechanically stable and does not dissolve or leach out over the useful lifetime of the defibrillator. A hot can defibrillator employing the polymeric coating avoids development of high polarization at the can/tissue interface and maintains a more uniform defibrillation threshold than conventional implantable defibrillators, thus increasing the feasibility of pectoral implantation, particularly in a “dry pocket” environment.

REFERENCES:
patent: 3357930 (1967-12-01), Marks et al.
patent: 3865615 (1975-02-01), Manly
patent: 4281669 (1981-08-01), MacGregor
patent: 4326532 (1982-04-01), Hammar
patent: 4355426 (1982-10-01), MacGregor
patent: 4459252 (1984-07-01), MacGregor
patent: 4515162 (1985-05-01), Yamamoto et al.
patent: 4585652 (1986-04-01), Miller et al.
patent: 4602637 (1986-07-01), Elmqvist et al.
patent: 4627836 (1986-12-01), MacGregor
patent: 4677989 (1987-07-01), Robblee
patent: 4717581 (1988-01-01), Robblee
patent: 4919135 (1990-04-01), Phillips, Jr. et al.
patent: 5203348 (1993-04-01), Dahl et al.
patent: 5227042 (1993-07-01), Zawodzinski et al.
patent: 5354790 (1994-10-01), Keusch et al.
patent: 5409696 (1995-04-01), Narayanan et al.
patent: 5411527 (1995-05-01), Alt
patent: 5473812 (1995-12-01), Morris et al.
patent: 5480416 (1996-01-01), Garcia et al.
patent: 5488768 (1996-02-01), Mar
patent: 5512055 (1996-04-01), Domb et al.
patent: 5520180 (1996-05-01), Uy et al.
patent: 5529579 (1996-06-01), Alt et al.
patent: 5576072 (1996-11-01), Hostettler et al.
patent: 5601607 (1997-02-01), Adams
patent: 5654030 (1997-08-01), Munshi et al.
patent: 5746616 (1998-05-01), Mar
patent: 5766527 (1998-06-01), Schidgen et al.
patent: 5845396 (1998-12-01), Altman et al.
patent: 5964794 (1999-10-01), Bolz et al.
patent: 6295474 (2001-09-01), Munshi
patent: 6718628 (2004-04-01), Munshi
patent: 0051354 (1982-05-01), None
patent: 0299698 (1989-01-01), None
patent: 0644904 (1995-03-01), None
patent: 2086217 (1997-08-01), None
patent: WO9205753 (1992-04-01), None
Ahlswede, K.M., et al., “Microvascular Endothelial Cell Sodding of 1-mm Expanded Polytetrafluoroethylene Vascular Grafts”,Arterioscler. Thromb., 14, 25-31, (1994).
Chang, Y., et al., “Assessment of an Epoxy-Filled Pericardial Patch With or Without Ionically Bound Heparin in a Canine Model”,Int. J. Artificial Organs, 20, 332-340, (1997).
Hirigoyen, M.B., et al., “Periadventitial Delivery of Heparin in the Prevention of Microvenous Thrombosis”,J. Oral Maxillofac. Surg., 54, 1097-1102, (1996).
Homsy, C.S., et al., “Tissue Ingrowth Implant Fixation by a Soft Porous Coating”,Proceedings of the 34th ACEMB, Shamrock Hilton Hotel, Houston, TX, p. 162, (Sep. 21-23, 198).
Julio, C.A., et al., “Blood Compatibility of Tubular Polymeric Materials Studied by Biological Surface Interactions”,Braz. J. Med. Biol. Res., 27, 2565-2568, (1994).
Keogh, J.R., et al., “Biocompatibility of Sulphonated Polyurethane Surfaces”,Biomater, 17, 1987-1994, (1996).
Narayanan, P.V., et al., “Radiofrequency Plasma Treated Polymeric Surfaces Having Immobilized Anti-Thrombogenic Agents”, U.S. Pat. No. 5409696, (1995).
Nimni, M.E., et al., “Chemically Modified Collagen: a Natural Biomaterial for Tissue Replacement”,J. Biomed. Mater. Res., 21, 741-771, (1987).
Tang, L., et al., “Fibrin (ogen) Mediates Acute Inflammatory Responses to Biomaterials”,J. Exp. Med., 178, 2147-2156, (1993).
Walton, D.G., et al., “Creation of Stable Poly(ethylene oxide) Surfaces on Poly(methyl methacrylate) Using Blends of Branched and Linear Polymers”,Macromolecules 30, 6947-6956, (1997).
Williams, S.K., et al., “Endothelial Cell Transplantation onto Polymeric Arteriovenous Grafts Evaluated Using a Canine Model”,J. Invest. Surg., 7, 503-517, (1994).
Breivik, K., “Clinical Evaluation of a Thin Biopolar Pacing Lead”,PACE vol. 20, (Mar. 1997),637-646.
Espadas-Torre, Cecilia, et al., “Thrombogenic Properties of Untreated and Poly(ethylene oxide)-Modified Polymeric Matrices Useful for Preparing Intraarterial Ion-Selective Electrodes”,Analytical Chemistry, 67, (Sep. 15, 1995),3108-3114.
Olsen, Douglas A., et al., “Thrombus Formation on Polymeric Materials II. Blood Compatible Surfaces”,Minnesota Medicine, 53, (Aug. 1970),877-884.
Dzagnidze, K., et al., “The Creation of New Polymeric Compositions with Improved Thromboresistent Properties and Their Evaluation in the Experiments in vitro”,Izv. Adad. Nauk Gruk. SSR, Ser. Khim., 15, (1989),306-9.
Espadas-Torre et al, “Thrombogenic Properties of Untreated and Poly(ethylene oxide)-Modified Polymeric Matrices Useful for preparing Intraarterial ion-Selective Electrodes,” Anal. Chem., 1995, vol. 67, pp. 3108-3114.

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